| Structure | Trade Name | Generic Name | 2006 Global Sales (Billion US$) |
Company | Indication |
 |
Lipitor | atorvastatin | 13.6 | Pfizer | High Cholesterol |
 |
Nexium | esomeprazole | 6.7 | AstraZeneca | Heartburn |
 |
Seretide/Advair | fluticasone/ salmeterol |
6.3 | GlaxoSmithKline | Asthma |
 |
Plavix | clopidogrel | 5.8 | Bristol-Myers Squibb / Sanofi-Aventis |
Heart Disease |
 |
Norvasc | amlodipine | 5.0 | Pfizer | Hypertension |
| Protein | Aranesp | darbepoetin alfa |
5.0 | Amgen | Anemia |
 |
Zyprexa | olanzapine | 4.7 | Eli Lilly | Bipolar Disorder |
 |
Risperdal | risperidone | 4.6 | Johnson & Johnson | Schizophrenia |
| Protein | Enbrel | etanercept | 4.5 | Amgen/Wyeth | Arthritis |
 |
Effexor | venlafaxine | 4.0 | Wyeth | Depression |
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Sales Data Source: IMS Intelligence.360