Cheminformatics Puzzler #2: Planar Chiral Paracyclophanes
Source: Duan, Ma, Xia, Liu, Ma, and Sun J. Org. Chem.
Without using 3D coordinates, represent the chirality of this class of planar chiral paracyclophanes (hint).
Cheminformatics Puzzler #1
How can the above atropisomers be represented without using explicit 3D coordinates?
Source: Clayden, Worrall, Moran, and Helliwell Angew. Chem. Int. Ed.
How Would Your Cheminformatics Tool Do This? 2
Source: Lunazzi, Mancinelli, and Mazzanti J. Org. Chem.
How Would Your Cheminformatics Tool Do This? 1
How Would Your Cheminformatics Tool Do This?
Reference: Favarger, Goujon-Ginglinger, Monchaud, and Lacour J. Org. Chem.
