An article by Thomas Engel honoring Johann Gasteiger has recently appeared in J. Chem. Inf. Model. Tucked between two pages of text is a fascinating full-color, full-page timeline of Bio- and Chem(o)informatics. It starts with the abacus in 3000 B.C. and Libavius' Alchemia in 1500 A.D. Near the end, it records the advent of virtual screening in 1998. Then, the very next event on this very large timeline happens in 2000 - it's the founding of the CDK project!